UCLA Micro and Nano Manufacturing Laboratory » contributor http://cjmems.seas.ucla.edu Wed, 08 May 2013 18:50:23 +0000 en hourly 1 http://wordpress.org/?v=3.0.1 Wyatt Nelson http://cjmems.seas.ucla.edu/?p=302 http://cjmems.seas.ucla.edu/?p=302#comments Mon, 11 Apr 2011 22:15:35 +0000 contributor http://cjmems.seas.ucla.edu/wordpress/?p=302
Bio:
Born on July 29, 1983 in Seattle, WA
Grew up in Kingston, WA
2006: B.S. Mechanical Engineering, Cornell University
2011: Ph.D. Mechanical Engineering, UCLA


Research Interests:
Electrowetting-on-dielectric (EWOD)
Microfluidics for point-of-care and high-throughput screening devices
Microelectromechanical Systems (MEMS) fabrication

 

Projects:
Monolithic EWOD chips
Surface-micromachined EWOD chips in the parallel-plate configuration have been demonstrated with 10 um gap heights.
Reference: W. C. Nelson and C.-J. Kim, “A Monolithic EWOD Chip by Surface Micromachining”, Technical Digest, Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head Island, SC, June 2010, pp. 158-161.

 

EWOD-actuated filament rheometer
A micromachined chip generates liquid filaments by electrostatic force for capillary breakup rheometry of microliter volumes.
Reference: W. C. Nelson, P. Kavehpour, and C.-J. Kim, “A Micro Extensional Filament Rheometer Enabled by EWOD”, Proc. IEEE Int. Conf. MEMS, Hong Kong, China, Jan. 2010, pp. 75-78.

 

Incubated MALDI-MS sample preparation using multifunctional EWOD electrodes
Multifunctional EWOD electrodes perform actuation, heating, and temperature sensing without complicated fabrication or operation.
Reference: W. C. Nelson, I. Peng, G.-A. Lee, J. A. Loo, R. L. Garrell, and C.-J. Kim, “Incubated Protein Reduction and Digestion on an Electrowetting-on-Dielectric Digital Microfluidic Chip for MALDI-MS,” Analytical Chemistry, Vol. 82, No. 23, December 2010, pp. 9932–9937.

 

Journal papers
W. C. Nelson and C.-J. Kim, “Droplet Actuation by Electrowetting-on-Dielectric: A Review,” Journal of Adhesion Science and Technology, In press.
W. C. Nelson, I. Peng, G.-A. Lee, J. A. Loo, R. L. Garrell, and C.-J. Kim, “Incubated Protein Reduction and Digestion on an Electrowetting-on-Dielectric Digital Microfluidic Chip for MALDI-MS,” Analytical Chemistry, Vol. 82, No. 23, December 2010, pp. 9932–9937.
J. L. Poulos, W. Nelson, T.-J. Jeon, C.-J. Kim, and J. J. Schmidt, “EWOD Based Microfluidics for Integrated Lipid Bilayer Formation and Ion Channel Measurement”, Applied Physics Letters, Vol. 95, Issue 1, July 2009, 013706 (3 pages) (doi: 10.1063/1.3167283).
Vishal Tandon, Sharath K. Bhagavatula, Wyatt C. Nelson, and Brian J. Kirby, “Zeta potential and electroosmotic mobility in microfluidic devices fabricated from hydrophobic polymers: 1. The origins of charge,” Electrophoresis, vol. 29(5), (2008), p. 1092-1101.

 

Conference papers
W. C. Nelson, M. Yen, P. Y. Keng, R. M. van Dam, and C.-J. Kim, “High Pressure EWOD Digital Microfluidics”, Proc. Int. Conf. Solid State Sensors, Actuators and Microsystems (Transducers ’09), June 2011, Beijing, China, (upcoming).
W. C. Nelson and C.-J. Kim, “A Monolithic EWOD Chip by Surface Micromachining”, Technical Digest, Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head Island, SC, June 2010, pp. 158-161.
W. C. Nelson, P. Kavehpour, and C.-J. Kim, “A Micro Extensional Filament Rheometer Enabled by EWOD”, Proc. IEEE Int. Conf. MEMS, Hong Kong, China, Jan. 2010, pp. 75-78.
W. C. Nelson, P. Sen, and C.-J. Kim, “Resistance of Droplets Sliding by EWOD Actuation”, Proc. Int. Conf. Solid State Sensors, Actuators and Microsystems (Transducers ’09), June 2009, Denver, CO, U.S.A., pp. 2014-2017.
W. C. Nelson, I. Peng, J. A. Loo, R. L. Garrell, and C.-J. Kim, “An EWOD Digital Microfluidic Chip with Integrated Localized Temperature Control for Multiplex Proteomics Sample Processing”, Proc. IEEE Int. Conf. MEMS, Jan. 2009, Sorrento, Italy, pp. 280-283.
]]> http://cjmems.seas.ucla.edu/?feed=rss2&p=302 0 Supin Chen http://cjmems.seas.ucla.edu/?p=297 http://cjmems.seas.ucla.edu/?p=297#comments Tue, 05 Apr 2011 18:18:13 +0000 contributor http://cjmems.seas.ucla.edu/wordpress/?p=297 Bio 2003-2004: Technician (PET detectors), Lawrence Berkeley National Laboratory 2005: B.S. Bioengineering, UC Berkeley 2005-2006: R&D engineer (neurovascular stents), Boston Scientific 2006- Graduate Student, UCLA Research interests Microfluidics, Electrowetting-on-dielectric (EWOD) Microelectromechanical Systems (MEMS) fabrication Medical devices: diagnostics, surgical instruments, imaging Automated chemical synthesis

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Projects:

On-chip purification after chemical synthesis
Removal of ions by planar surface trapping with EWOD mixing as an on-chip alternative to purification columns.
EWOD radiotracer synthesis for positron emission tomography (PET)
Automated chemical synthesis of various PET tracers using an EWOD (electrowetting-on-dielectric) microfluidic device with integrated resistive heaters.
PCB EWOD device for soft-printing delivery onto cell cultures
Robust 16 x 16 EWOD electrode PCB devices deliver arrays of droples containing transcription factors onto cell cultures for synthetic biology control.
Nanogel encapsulation to improve EWOD operation with proteins
Reduced protein adsorption onto hydrophobic surfaces by encapsulating individual protein molecules in polymer nanogels.

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Journal Papers:

Pei-Yuin Keng, Supin Chen, Huijiang Ding, Saman Sadeghi, Gaurav J. Shah, Alex Dooraghi, Michael E. Phelps, Nagichettiar Satyamurthy, Arion F. Chatziioannou, Chang-Jin “CJ” Kim, and R. Michael van Dam, “Micro-chemical synthesis of molecular probes on an electronic microfluidic device”, Proceedings of the National Academy of Sciences, Vol. 84, No. 4, (2012), pp. 1915-1923.
Saman Sadeghi, Huijiang Ding, Gaurav J. Shah, Supin Chen, Pei-Yuin Keng, Chang-Jin “CJ” Kim, and R. Michael van Dam, “On chip droplet characterization: A practical, high-sensitivity measurement of droplet impedance in digital microfluidics”, Analytical Chemistry, Vol. 84, No. 4, (2012), pp. 1915-1923.
Takeshi Kawano, Dane Christensen, Supin Chen, Chung Yeung Cho, and Liwei Lin, “Formation and characterization of silicon/carbon nanotube/silicon heterojunctions by local synthesis and assembly”, Applied Physics Letters, Vol. 89, No. 16, (20120), 163510.

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Conference Papers:

2012
Supin Chen, Mohammed  R. Javed, Jack Lei, Hee-Kwon Kim, Graciela Flores, R. Michael van Dam, Pei-Yuin Keng, and Chang-Jin “CJ” Kim, “Synthesis of diverse tracers on EWOD microdevice for positron emission tomography (PET)”, Technical Digest of the Solid-State Sensor and Actuator workshop, Hilton Head Island, South Carolina, 6/3-6/7, Transducer Research Foundayion, (2012), (To appear).
Pei-Yuin Keng, Supin Chen, Alex Dooraghi, Mark Lazari, Mohammed R. Javed, Arion F. Chatziioannou, Chang-Jin “CJ” Kim, R. Michael van Dam, “In situ Čerenkov imaging for optimization of radiochemistry on chip”, Proceedings of the 4th International Symposium on Microchemistry and Microsystems, Hsinchu, Taiwan, 6/10-6/13, (2012), (To appear).
Gaurav J. Shah, Pei-Yuin Keng, Supin Chen, Mohammed R. Javed, Hui-Jiang Ding, Sam Sadeghi, Chang-Jin Kim, and R. Michael van Dam, “Integrated digital microchemistry platform: Automation of multi-reagent loading, on-chip high-temperature reactions, and product extraction”, Proceedings of the 4th International Symposium on Microchemistry and Microsystems, Hsinchu, Taiwan, 6/10-6/13, (2012), (To appear).
2011
Supin Chen, Pei-Yuin Keng, R. Michael van Dam, and Chang-Jin “CJ” Kim, “Synthesis of 18F-labeled probes on EWOD platform for positron emission tomography (PET) preclinical imaging”, Proceedings of the International Conference of MEMS, Cancun, Mexico, 1/23-1/27, IEEE, (2011), pp. 980-983.
Pei-Yuin Keng, Supin Chen, Michael E. Phelps, Nagichettiar Satyamurthy, Chang-Jin “CJ” Kim, R. Michael van Dam, “Toward on-demand production of diverse PET tracers: Repeatable, multi-step synthesis of [18F]FDG on a compact, electronically-actuated droplet-based microfluidic platform”, Society of Nuclear Medicine 2912 Annual Meeting, San Antonio, Texas, 6/4-6/7, (2011).
Pei-Yuin Keng, Supin Chen, Hui-Jiang ding, Sam Sadeghi, Michael E. Phelps, Nagichettiar Satyamurthy, Chang-Jin “CJ” Kim, and R. Michael van Dam, “Electrowetting on dielectric digital microfluidic chips for multistep radiosynthesis of PET tracers”, 19th International Symposium on Radiopharmaceutical Sciences, Amsterdam, The Netherlands, 8/28-9/2, (2011).
Gaurav J. Shah, Supin Chen, Pei-Yuin Keng, Sam Sadeghi, Chang-Jin Kim, R. Michael van Dam, “Automation of a digital microfluidic system for repeatable radiosynthesis of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) and other tracers”, 2011 World Molecular Imaging Congress, San Diego, California, 9/7-9/10, (2011).
Gaurav J. Shah, Hui-jiang Ding, Sam Sadeghi, Supin Chen, Chang-Jin Kim, and R. Michael van Dam, “Milliliter-to-microliter platform for on-demand loading of aqueous and non-aqueous droplets to digital microfluidics”, Proceedings of the 16th International Solid-State Sensors, Actuators, and Microsystems Conference, Beijing, China, 6/5-6/9, (2011) pp. 1260-1263.
Gaurav J. Shah, Sam Sadeghi, Hui-Jiang Ding, Supin Chen, R. Michael van Dam, “Impedance-based droplet volume and concentration measurement in digital microfluidics”, Proceedings to MicroTAS 2011, the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, Washington, 10/2-10/6,  Chemical and Biological Microsystems Society, (2010), pp. 1308-1310.
Hui-Jiang Ding, Sam Sadeghi, Pei-Yuin Keng, Supin Chen, Gaurav J. Shah, Chang-Jin “CJ” Kim, R. Michael van Dam, “Accurate dispensing of volatile reagents on demand for EWOD chips”, Proceedings to MicroTAS 2011, the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, Washington, 10/2-10/6,  Chemical and Biological Microsystems Society, (2010), pp. 227-229.
2010
Supin Chen, Hui-Jiang Ding, Gaurav J. Shah, R. Michael van Dam, and Chang-Jin “CJ” Kim, “EWOD microdevices for synthesis of 18F-labeled tracers for positron emission tomography (PET)”, Technical Digest of the Solid-State Sensor and Actuator workshop, Hilton Head Island, South Carolina, 6/6-6/10, Transducer Research Foundayion, (2010), pp. 37-40.
Pei Yuin Keng, Supin Chen, Hui-Jiang Ding, Sam Sadeghi, Michael E. Phelps, Nagichettiar Satyamurthy, Chang-Jin “CJ” Kim, and R. Michael van Dam, “Electrowetting on dielectric digital microfluidic chips for multistep radiosynthesis of PET tracers”, Proceedings to MicroTAS 2010, the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Groningen, The Netherlands, 10/3-10/7,  Chemical and Biological Microsystems Society, (2010), pp. 668-670.
]]> http://cjmems.seas.ucla.edu/?feed=rss2&p=297 0 Tingyi (Leo) Liu http://cjmems.seas.ucla.edu/?p=248 http://cjmems.seas.ucla.edu/?p=248#comments Fri, 04 Mar 2011 18:51:03 +0000 contributor http://cjmems.seas.ucla.edu/wordpress/?p=248 Biosketch:

Tingyi (Leo) Liu received Bachelor of Engineering degree (with honor) from Zhejiang University, Hangzhou China, in 2009. He is currently working toward the PhD degree in mechanical engineering at University of California, Los Angeles (UCLA). Working in the Micro and Nano Manufacturing Laboratory, UCLA, his research interests include engineering designs utilizing capillarity, liquid-metal-based micro devices, and micro gyroscope systems. Prior to working on the micro rotary stage project, Mr. Liu has worked on the characterization of non-toxic liquid-metal alloy Galinstan® and presented the related paper in IEEE Micro-Electromechanical Systems 2010 conference (MEMS’10) in Hong Kong, China.

]]> http://cjmems.seas.ucla.edu/?feed=rss2&p=248 0 Yi Zhou http://cjmems.seas.ucla.edu/?p=252 http://cjmems.seas.ucla.edu/?p=252#comments Fri, 04 Mar 2011 18:50:45 +0000 contributor http://cjmems.seas.ucla.edu/wordpress/?p=252

EDUCATION

2010-Present      Ph.D. Student in Mechanical Engineering, University of California, Los Angeles

  • Graduate Student Researcher

2006-2010           B.S. in Microelectronics, Peking University, Beijing, China

RESEARCH EXPERIENCE

2010-Present

  • Graduate Student Researcher at Micro/Nano Manufacturing Laboratory, UCLA
  • Advisor: Professor Chang-Jin “CJ” Kim

2007-2010

  • Undergraduate Research Assistant at MEMS Research Center, The National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Institute of Microelectronics, Peking University
  • Advisor: Professor Wengang Wu

PUBLICATIONS

  • C. Qian, C. Ni, Y. L. Zhang, Y. Zhou, W. G. Wu, J. Xu, and Y. L. Hao, “A HIGHLY-ORDERED THREE-DIMENSIONAL PETAL-LIKE ARRAYED STRUCTURE FOR HIGHLY SURFACE-ENHANCED RAMAN SCATTERING”, Proc. MEMS 2010, the 23rd IEEE International Conference on Micro-Electro-Mechanical Systems, Hong Kong, China, Jan. 24-28, pp. 875-878.
  • Yi Zhou, Chuang Qian, Wei Wang, Wengang Wu, “PARYLENE BASED TWO-DIMENSIONAL OPEN MICROFLUIDIC CHANNELS”, Proc. MicroTAS 2009, the 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Jeju, Korea, Nov. 1-5, pp. 884-886.
  • Yi Zhou, Fei Ding, Chao Ni, Wei Wang, Wengang Wu, “Bottom-up fabrication of special parylene films based on selective growth on Au-coated surface,” Proc. IEEE NEMS 2009, the 4th IEEE International Conference of Nano/Micro Engineered and Molecular Systems, Shenzhen, China, Jan. 5-8, pp.441-444.
]]> http://cjmems.seas.ucla.edu/?feed=rss2&p=252 0 Guangyi Sun http://cjmems.seas.ucla.edu/?p=280 http://cjmems.seas.ucla.edu/?p=280#comments Tue, 22 Feb 2011 23:14:18 +0000 contributor http://cjmems.seas.ucla.edu/wordpress/?p=280

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