DNA based Diagonistics and DNA Microarrays

Description

DNA Microarray

A shape-encoded particle (SEP) is used as a substrate for biochemical probe (such as DNA or protein) attachment and identification. Its application involves large-scale genomic/proteomic analysis of multiple data based on shape-recognizable microparticles. Our goal is to provide a simple tool to greatly simplify the DNA microarray procedure, and allow more flexibility and better quality control in experimental design.

Silicon Pin in Printing

A micromachined silicon pin was developed to serves as a novel contact-printing tool. More specific application is in the DNA and protein microarray field for small and precise droplet printing onto a solid support. Our goal is to develop low cost, high performance silicon pins as simple replacement of the stainless-steel pins used in typical microarray robots.

Current Members:

Jane Tsai

Past Members:

Publications

"Shape-encoded Particle for DNA Analysis"
Jane Gin Fai Tsai, Zugen Chen, Barry Merriman, Stanley Nelson, and Chang-Jin "CJ" Kim
IEEE Transducers '03 Conf. Boston, Mass. June 8-12, 2003. pp. 1239-1242.
PDF format

"A Silicon-micromachined Pin for Contact Droplet Printing"
Jane Gin Fai Tsai, Zugen Chen, Stanley Nelson, and Chang-Jin .CJ. Kim
IEEE Conf. MEMS, Kyoto, Japan, Jan. 2003, pp. 295-298.
PDF format